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To the best of our knowledge, this study was the first to investigate HTN-related SNPs using the K-CHIP in a Korean population.Therefore, the objective of the present study was to explore HTN-related SNPs using the K-CHIP, to identify the SNP most strongly associated with BP, and to determine whether Body weight (UM0703581; Tanita, Tokyo, Japan) and height (GL-150; G-Tech International, Uijeongbu, Korea) were measured in lightly clothed subjects without shoes, and body mass index (BMI) values were calculated (kg/m).The objective of the present study was to determine whether 0.001].



Waist circumference was measured directly on the skin at the umbilical level after normal expiration with the subject in an upright standing position.

Hip circumference was measured at the protruding part of the hip in standing subjects using a plastic measuring tape with measurements to the nearest 0.1 cm.

The gels were scanned using a GS-800 Calibrated Imaging Densitometer (Bio-Rad Laboratories, Hercules, CA, USA).

Plasma ox-LDL was estimated using an enzyme immunoassay (Mercodia AB, Uppsala, Sweden), and the resulting color reaction was determined at 450 nm on a Wallac Victor2 multilabel counter (Perkin-Elmer Life Sciences, Boston, MA, USA).

Since whole-genome sequencing requires very high calculation capacity and cost and commercial chips are designed for Western populations, whose genomic variants differ from Asian populations, the K-CHIP is more suitable for the discovery and identification of Korean population-specific SNPs related to disease occurrence [].


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